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Plasma interleukin responses as predictors of outcome stratification in patients after major trauma: a prospective observational two centre study (2023)
Journal Article
Jones, M. A., Hanison, J., Apreutesei, R., Allarakia, B., Namvar, S., Ramaswamy, D. S., …Nirmalan, N. (2023). Plasma interleukin responses as predictors of outcome stratification in patients after major trauma: a prospective observational two centre study. Frontiers in Immunology, 14, 1276171. https://doi.org/10.3389/fimmu.2023.1276171

Background and objectives: There is a need to develop objective risk stratification tools to define efficient care pathways for trauma patients. Biomarker-based point of care testing may strengthen existing clinical tools currently available for this... Read More about Plasma interleukin responses as predictors of outcome stratification in patients after major trauma: a prospective observational two centre study.

Authentic Pathology Specimen Reception: A Valuable Resource for Developing Biomedical Science Student Competencies and Employability (2023)
Journal Article
Hussain, T., Namvar, S., & Jones, M. (2023). Authentic Pathology Specimen Reception: A Valuable Resource for Developing Biomedical Science Student Competencies and Employability. British Journal of Biomedical Science, 80, 11731. https://doi.org/10.3389/bjbs.2023.11731

Background/Introduction: The pathology specimen reception is fundamental to the services provided by Biomedical Science laboratories worldwide. To ensure patient safety and that samples are of adequate quality to send for analysis, prospective Biomed... Read More about Authentic Pathology Specimen Reception: A Valuable Resource for Developing Biomedical Science Student Competencies and Employability.

Aspergillus fumigatus —host interactions mediating airway wall remodelling in asthma (2022)
Journal Article
Namvar, S., Labram, B., Rowley, J., & Herrick, S. (2022). Aspergillus fumigatus —host interactions mediating airway wall remodelling in asthma. Journal of Fungi, 8(2), e159. https://doi.org/10.3390/jof8020159

Asthma is a chronic heterogeneous respiratory condition that is mainly associated with sensitivity to airborne agents such as pollen, dust mite products and fungi. Key pathological features include increased airway inflammation and airway wall remode... Read More about Aspergillus fumigatus —host interactions mediating airway wall remodelling in asthma.

Co-creation and empowerment: pathways to better student engagement (2021)
Other
Namvar, S., Greensmith, D., & Nirmalan, N. (2021). Co-creation and empowerment: pathways to better student engagement. THE Campus

Progression and employability are at the forefront of current conversations in higher education, with much effort invested in developing complex interventions to improve graduate outcomes. Pedagogy research indicates that factors such as a sense of b... Read More about Co-creation and empowerment: pathways to better student engagement.

Differential proinflammatory responses to Aspergillus fumigatus by airway epithelial cells in vitro are protease dependent (2021)
Journal Article
Rowley, J., Namvar, S., Gago, S., Labram, B., Bowyer, P., Richardson, M., & Herrick, S. (2021). Differential proinflammatory responses to Aspergillus fumigatus by airway epithelial cells in vitro are protease dependent. Journal of Fungi, 7(6), e468. https://doi.org/10.3390/jof7060468

Aspergillus fumigatus is an important human respiratory mould pathogen. In addition to a barrier function, airway epithelium elicits a robust defence against inhaled A. fumigatus by initiating an immune response. The manner by which A. fumigatus init... Read More about Differential proinflammatory responses to Aspergillus fumigatus by airway epithelial cells in vitro are protease dependent.

Endothelin-1 mediates Aspergillus fumigatus induced airway inflammation and remodelling (2019)
Journal Article
Labram, B., Namvar, S., Hussell, T., & Herrick, S. (2019). Endothelin-1 mediates Aspergillus fumigatus induced airway inflammation and remodelling. Clinical and Experimental Allergy, 49(6), 861-873. https://doi.org/10.1111/cea.13367

BACKGROUND: Asthma is a chronic inflammatory condition of the airways and patients sensitised to airborne fungi such as Aspergillus fumigatus have more severe asthma. Thickening of the bronchial subepithelial layer is a contributing factor to asthma... Read More about Endothelin-1 mediates Aspergillus fumigatus induced airway inflammation and remodelling.

Functional molecules in mesothelial to mesenchymal transition revealed by transcriptome analyses (2018)
Journal Article
Namvar, S., Woolf, A., Zeef, L., Wilm, T., Wilm, B., & Herrick, S. (2018). Functional molecules in mesothelial to mesenchymal transition revealed by transcriptome analyses. Journal of Pathology, 245(4), 491-501. https://doi.org/10.1002/path.5101

Peritoneal fibrosis is a common complication of abdominal and pelvic surgery, and can also be triggered by peritoneal dialysis, resulting in treatment failure. In these settings, fibrosis is driven by activated myofibroblasts that are considered to b... Read More about Functional molecules in mesothelial to mesenchymal transition revealed by transcriptome analyses.

Dietary fat and corticosterone levels are contributing factors to meal anticipation (2016)
Journal Article
Namvar, S., Gyte, A., Denn, M., Leighton, B., & Piggins, H. (2016). Dietary fat and corticosterone levels are contributing factors to meal anticipation. American Journal of Physiology, 310(8), R711-R723. https://doi.org/10.1152/ajpregu.00308.2015

Daily restricted access to food leads to the development of food anticipatory activity and metabolism, which depends upon an as yet unidentified food-entrainable oscillator(s). A premeal anticipatory peak in circulating hormones, including corticoste... Read More about Dietary fat and corticosterone levels are contributing factors to meal anticipation.

Aspergillus fumigatus proteases, Asp f 5 and Asp f 13, are essential for airway inflammation and remodelling in a murine inhalation model (2014)
Journal Article
Namvar, S., Warn, P., Farnell, E., Bromley, M., Fraczek, M., Bowyer, P., & Herrick, S. (2015). Aspergillus fumigatus proteases, Asp f 5 and Asp f 13, are essential for airway inflammation and remodelling in a murine inhalation model. Clinical and Experimental Allergy, 45(5), 982-993. https://doi.org/10.1111/cea.12426

BACKGROUND: In susceptible individuals, exposure to Aspergillus fumigatus can lead to the development of atopic lung diseases such as allergic bronchopulmonary aspergillosis (ABPA) and severe asthma with fungal sensitization (SAFS). Protease allergen... Read More about Aspergillus fumigatus proteases, Asp f 5 and Asp f 13, are essential for airway inflammation and remodelling in a murine inhalation model.

A riot of rhythms : neuronal and glial circadian oscillators in the mediobasal hypothalamus (2009)
Journal Article
Guilding, C., Hughes, A., Brown, T., Namvar, S., & Piggins, H. (2009). A riot of rhythms : neuronal and glial circadian oscillators in the mediobasal hypothalamus. Molecular Brain, 2(28), https://doi.org/10.1186/1756-6606-2-28

Background: In mammals, the synchronized activity of cell autonomous clocks in the suprachiasmatic nuclei (SCN) enables this structure to function as the master circadian clock, coordinating daily rhythms in physiology and behavior. However, the domi... Read More about A riot of rhythms : neuronal and glial circadian oscillators in the mediobasal hypothalamus.

Practical examples of building graduate capital and project co-creation: Towards improved employability
Presentation / Conference
project co-creation: Towards improved employability. Presented at Employability Symposium 2022

The University of Salford is home to a diverse community of learners, with a large percentage of students from BAME, disabled and low socioeconomic backgrounds. The Biomedical Sciences (BMS) programme holds a particularly high proportion of BAME stud... Read More about Practical examples of building graduate capital and project co-creation: Towards improved employability.