Circular dichroism to determine binding mode and affinity of ligand-DNA interactions
(2007)
Journal Article
Garbett, N., Ragazzon, P., & Chaires, J. (2007). Circular dichroism to determine binding mode and affinity of ligand-DNA interactions. Nature Protocols, 2(12), 3166-3172
Circular dichroism (CD) is a useful technique for an assessment of DNA-binding mode, being a more accessible, low-resolution complement to NMR and X-ray diffraction methods. Ligand-DNA interactions can be studied by virtue of the interpretation of in... Read More about Circular dichroism to determine binding mode and affinity of ligand-DNA interactions.