Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions
(2013)
Journal Article
Aziz, A., Baxter, E., Edwards, C., Cheong, C., Ito, M., Bench, A., …Green, A. (2013). Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions. Journal of Clinical Investigation, 123(5), 2169-2182. https://doi.org/10.1172/JCI66113
Large regions of recurrent genomic loss are common in cancers; however, with a few well-characterized exceptions, how they contribute to tumor pathogenesis remains largely obscure. Here we identified primate-restricted imprinting of a gene cluster on... Read More about Cooperativity of imprinted genes inactivated by acquired chromosome 20q deletions.