All Outputs (31)

A novel morbillivirus and a novel betaherpesvirus infecting the Wood Mouse in the UK (2024)
Journal Article
Jackson, J. A. (in press). A novel morbillivirus and a novel betaherpesvirus infecting the Wood Mouse in the UK. #Journal not on list, 68, 13177. https://doi.org/10.3389/av.2024.13177

A novel morbillivirus and a novel betaherpesvirus are reported in the Wood Mouse (Apodemus sylvaticus) in the western United Kingdom (UK). The two viruses were found coinfecting an underweight host with abnormalities of the liver and were detected vi... Read More about A novel morbillivirus and a novel betaherpesvirus infecting the Wood Mouse in the UK.

Large-bodied gastric spirurids (Nematoda, Spirurida) predict structure in the downstream gastrointestinal helminth community of wild spiny mice (Acomys dimidiatus) (2024)
Journal Article
Behnke, J., Jackson, J., Gilbert, F., Mohallal, E., & Bajer, A. (in press). Large-bodied gastric spirurids (Nematoda, Spirurida) predict structure in the downstream gastrointestinal helminth community of wild spiny mice (Acomys dimidiatus). Parasitology,

The dominant helminths infecting spiny mice (Acomys dimidiatus) in the montane wadis of the Sinai Peninsula of Egypt are spirurid nematodes, notably Protospirura muricola and Mastophorus muris. Both are relatively large robust stomach worms that accu... Read More about Large-bodied gastric spirurids (Nematoda, Spirurida) predict structure in the downstream gastrointestinal helminth community of wild spiny mice (Acomys dimidiatus).

Lunar-linked biorhythms in the immune system of freshwater three-spined stickleback (2024)
Journal Article
Jackson, J. A., Stewart, A., & Cable, J. (2024). Lunar-linked biorhythms in the immune system of freshwater three-spined stickleback. #Journal not on list, 3(1), Article kyae007. https://doi.org/10.1093/discim/kyae007

Immune responses are widely accepted to be under circadian regulation via a molecular clock, with many practical consequences, but much less is known of how other biorhythms could affect the immune system. In this study we search for lunar rhythms (c... Read More about Lunar-linked biorhythms in the immune system of freshwater three-spined stickleback.

Remotely sensed localised primary production anomalies predict the burden and community structure of infection in long‐term rodent datasets (2023)
Journal Article
Jackson, J. A., Bajer, A., Behnke-Borowczyk, J., Gilbert, F., Grzybek, M., Alsarraf, M., & Behnke, J. (in press). Remotely sensed localised primary production anomalies predict the burden and community structure of infection in long‐term rodent datasets. Global Change Biology, https://doi.org/10.1111/gcb.16898

The increasing frequency and cost of zoonotic disease emergence due to global change have led to calls for the primary surveillance of wildlife. This should be facilitated by the ready availability of remotely sensed environmental data, given the imp... Read More about Remotely sensed localised primary production anomalies predict the burden and community structure of infection in long‐term rodent datasets.

Early‐life immune expression profiles predict later‐life health and fitness in a wild rodent (2023)
Journal Article
Wanelik, K. M., Begon, M., Bradley, J. E., Friberg, I. M., Taylor, C. H., Jackson, J. A., & Paterson, S. (2023). Early‐life immune expression profiles predict later‐life health and fitness in a wild rodent. Molecular Ecology, 32(13), 3471-3482. https://doi.org/10.1111/mec.16950

Individuals differ in the nature of the immune responses they produce, affecting dis-ease susceptibility and ultimately health and fitness. These differences have been hypothesized to have an origin in events experienced early in... Read More about Early‐life immune expression profiles predict later‐life health and fitness in a wild rodent.

Discrete patterns of microbiome variability across timescales in a wild rodent population (2023)
Journal Article
Fenn, J., Taylor, C., Goertz, S., Wanelik, K. M., Paterson, S., Begon, M., …Bradley, J. (2023). Discrete patterns of microbiome variability across timescales in a wild rodent population. BMC microbiology, 23(1), https://doi.org/10.1186/s12866-023-02824-x

Mammalian gastrointestinal microbiomes are highly variable, both within individuals and across populations, with
changes linked to time and ageing being widely reported. Discerning patterns of change in wild mammal popula-
tions can therefore prove... Read More about Discrete patterns of microbiome variability across timescales in a wild rodent population.

Effects of an IgE receptor polymorphism acting on immunity, susceptibility to infection, and reproduction in a wild rodent (2023)
Journal Article
Wanelik, K. M., Begon, M., Bradley, J. E., Friberg, I. M., Jackson, J. A., Taylor, C. H., & Paterson, S. (2023). Effects of an IgE receptor polymorphism acting on immunity, susceptibility to infection, and reproduction in a wild rodent. eLife, 12, https://doi.org/10.7554/elife.77666

The genotype of an individual is an important predictor of their immune function, and subsequently, their ability to control or avoid infection and ultimately contribute offspring to the next generation. However, the same genotype, subjected to diffe... Read More about Effects of an IgE receptor polymorphism acting on immunity, susceptibility to infection, and reproduction in a wild rodent.

Living with chronic infection: persistent immunomodulation during avirulent haemoparasitic infection in a wild rodent (2022)
Journal Article
Taylor, C., Friberg, I., Jackson, J., Arriero, E., Begon, M., Wanelik, K., …Bradley, J. (2022). Living with chronic infection: persistent immunomodulation during avirulent haemoparasitic infection in a wild rodent. Molecular Ecology, https://doi.org/10.1111/mec.16819

Apicomplexans are a protozoan phylum of obligate parasites which may be highly virulent during acute infections, but may also persist as chronic infections which appear to have little fitness cost. Babesia microti is an apicomplexan haemoparasite tha... Read More about Living with chronic infection: persistent immunomodulation during avirulent haemoparasitic infection in a wild rodent.

Carolinensis minutus (Dujardin, 1845) Travassos 1937 (Nematoda, Heligmonellidae) in Microtus agrestis in the United Kingdom (2022)
Journal Article
Jackson, J., & Friberg, I. (2022). Carolinensis minutus (Dujardin, 1845) Travassos 1937 (Nematoda, Heligmonellidae) in Microtus agrestis in the United Kingdom. Check List, 18(4), 845-848. https://doi.org/10.15560/18.4.845

The heligmonellid nematode Carolinensis minutus (Dujardin, 1845) Travassos, 1937 is recorded for the first time in Microtus agrestis (Linnaeus, 1761) in the United Kingdom. Small heligmosomoid specimens were recovered from a M. agrestis vole inhabiti... Read More about Carolinensis minutus (Dujardin, 1845) Travassos 1937 (Nematoda, Heligmonellidae) in Microtus agrestis in the United Kingdom.

Some observations on meaningful and objective inference in radioecological field studies (2022)
Journal Article
Jackson, J., Antwis, R., Beresford, N. A., & Wood, M. (2022). Some observations on meaningful and objective inference in radioecological field studies. Journal of Animal Ecology, 91(7), 1546-1553. https://doi.org/10.1111/1365-2656.13743

Anthropogenic releases of radiation are of ongoing importance for environmental protection, but the radiation doses at which natural systems begin to show effects are controversial. More certainty is required in this area to achieve optimal regulatio... Read More about Some observations on meaningful and objective inference in radioecological field studies.

Impacts of radiation exposure on the bacterial and fungal microbiome of small mammals in the Chernobyl Exclusion Zone (2021)
Journal Article
Antwis, R., Beresford, N., Jackson, J., Fawkes, R., Barnett, C., Potter, E., …Wood, M. (2021). Impacts of radiation exposure on the bacterial and fungal microbiome of small mammals in the Chernobyl Exclusion Zone. Journal of Animal Ecology, 90(9), 2172-2187. https://doi.org/10.1111/1365-2656.13507

Environmental impacts of the 1986 Chernobyl Nuclear Power Plant accident are much debated, but the effects of radiation on host microbiomes have received little attention to date.

We present the first analysis of small mammal gut microbiome from t... Read More about Impacts of radiation exposure on the bacterial and fungal microbiome of small mammals in the Chernobyl Exclusion Zone.

Fungal microbiomes are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome (2021)
Other
Harrison, X., McDevitt, A., Dunn, J., Griffiths, S., Benvenuto, C., Birtles, R., …Antwis, R. (2021). Fungal microbiomes are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome

Interactions between hosts and their resident microbial communities are a fundamental component of fitness for both agents. Though recent research has highlighted the importance of interactions between animals and their bacterial communities, compara... Read More about Fungal microbiomes are determined by host phylogeny and exhibit widespread associations with the bacterial microbiome.

Long-term trends in helminth infections of wood mice (Apodemus sylvaticus) from the vicinity of Malham Tarn in North Yorkshire, England (2020)
Journal Article
Behnke, J., Rogan, M., Craig, P., Jackson, J., & Hide, G. (2021). Long-term trends in helminth infections of wood mice (Apodemus sylvaticus) from the vicinity of Malham Tarn in North Yorkshire, England. Parasitology, 184(4), 451-463. https://doi.org/10.1017/S0031182020002243

Helminth infections in wood mice (n=483), trapped over a period of 26 years in the woods
surrounding Malham Tarn in N. Yorkshire, were analysed. Although ten species of helminths
were identified, the overall mean species richness was 1.01 species/m... Read More about Long-term trends in helminth infections of wood mice (Apodemus sylvaticus) from the vicinity of Malham Tarn in North Yorkshire, England.

Partitioning the environmental drivers of immunocompetence (2020)
Journal Article
Jackson, J., Friberg, I., Hablutzel, P., Masud, N., Stewart, A., Synnott, R., & Cable, J. (2020). Partitioning the environmental drivers of immunocompetence. Science of the Total Environment, 747, 141152. https://doi.org/10.1016/j.scitotenv.2020.141152

By determining susceptibility to disease, environment-driven variation in immune responses can affect the health, productivity and fitness of vertebrates. Yet how the different components of the total environment control this immune variation is rema... Read More about Partitioning the environmental drivers of immunocompetence.

Transcriptome-wide analysis reveals different categories of response to a standardised immune challenge in a wild rodent (2020)
Journal Article
Wanelik, K., Begon, M., Arriero, E., Bradley, J., Friberg, I., Jackson, J., …Paterson, S. (2020). Transcriptome-wide analysis reveals different categories of response to a standardised immune challenge in a wild rodent. Scientific reports, 10(1), 7444. https://doi.org/10.1038/s41598-020-64307-7

Individuals vary in their immune response and, as a result, some are more susceptible to infectious disease than others. Little is known about the nature of this individual variation in natural populations, or which components of immune pathways are... Read More about Transcriptome-wide analysis reveals different categories of response to a standardised immune challenge in a wild rodent.

Not going with the flow : locomotor activity does not constrain immunity in a wild fish (2019)
Journal Article
Masud, N., Synnott, R., Hablützel, P., Friberg, I., Cable, J., & Jackson, J. (2019). Not going with the flow : locomotor activity does not constrain immunity in a wild fish. Ecology and Evolution, 9(21), 12089-12098. https://doi.org/10.1002/ece3.5658

Immunity is a central component of fitness in wild animals, but its determinants are poorly understood. In particular, the importance of locomotory activity as a constraint on immunity is unresolved. Using a piscine model (Gasterosteus aculeatus) we... Read More about Not going with the flow : locomotor activity does not constrain immunity in a wild fish.

Diet in the driving seat: natural diet-immunity-microbiome interactions in wild fish (2019)
Journal Article
Friberg, I., Taylor, J., & Jackson, J. (2019). Diet in the driving seat: natural diet-immunity-microbiome interactions in wild fish. Frontiers in Immunology, 10(243), https://doi.org/10.3389/fimmu.2019.00243

Natural interactions between the diet, microbiome and immunity are largely unstudied. Here we employ wild three-spined
sticklebacks as a model, combining field observations with complementary experimental manipulations of diet designed to mimic
sea... Read More about Diet in the driving seat: natural diet-immunity-microbiome interactions in wild fish.

The cost of infection : Argulus foliaceus and its impact on the swimming performance of the three-spined stickleback (Gasterosteus aculeatus) (2018)
Journal Article
Stewart, A., Hunt, R., Mitchell, R., Muhawenimana, V., Wilson, C., Jackson, J., & Cable, J. (2018). The cost of infection : Argulus foliaceus and its impact on the swimming performance of the three-spined stickleback (Gasterosteus aculeatus). Interface, 15(147), https://doi.org/10.1098/rsif.2018.0571

For fish, there can be multiple consequences of parasitic infections, including the physical impacts on swimming and the pathological costs of infection. This study utilised the three-spined stickleback (Gasterosteus aculeatus) and the ectoparasitic... Read More about The cost of infection : Argulus foliaceus and its impact on the swimming performance of the three-spined stickleback (Gasterosteus aculeatus).

Physical cues controlling seasonal immune allocation in a naturally-occurring vertebrate (2018)
Journal Article
Stewart, A., Hablützel, P., Watson, H., Brown, M., Friberg, I., Cable, J., & Jackson, J. (2018). Physical cues controlling seasonal immune allocation in a naturally-occurring vertebrate. Frontiers in Immunology, 9, 582. https://doi.org/10.3389/fimmu.2018.00582

Seasonal patterns in immunity are frequently observed in vertebrates but are poorly understood. Here we focussed on a natural piscine model, the three-spined stickleback (Gasterosteus aculeatus), and asked how seasonal immune allocation is driven by... Read More about Physical cues controlling seasonal immune allocation in a naturally-occurring vertebrate.

Physiological, but not fitness, effects of two interacting haemoparasitic infections in a wild rodent (2018)
Journal Article
Taylor, C., Wanelik, K., Friberg, I., Lowe, A., Hall, A., Ralli, C., …Bradley, J. (2018). Physiological, but not fitness, effects of two interacting haemoparasitic infections in a wild rodent. International Journal for Parasitology, 48(6), 463-471. https://doi.org/10.1016/j.ijpara.2017.11.006

In contrast to the conditions in most laboratory studies, wild animals are routinely challenged by multiple infections at once, and these infections can interact in complex ways. This means that the impact of a parasite on its host’s physiology and f... Read More about Physiological, but not fitness, effects of two interacting haemoparasitic infections in a wild rodent.