Prof Geoff Hide's Outputs (7)

PAG3 promotes the differentiation of bloodstream forms in Trypanosoma brucei and reveals the evolutionary relationship among the Trypanozoon trypanosomes (2022)
Journal Article
Wen, Y., Tang, H., Cai, X., Wu, N., Xu, J., Su, B., …Lai, D. (2022). PAG3 promotes the differentiation of bloodstream forms in Trypanosoma brucei and reveals the evolutionary relationship among the Trypanozoon trypanosomes. Frontiers in Cellular and Infection Microbiology, 12, https://doi.org/10.3389/fcimb.2022.1021332

Introduction: Trypanosoma brucei, T. evansi and T. equiperdum are members of the subgenus Trypanozoon and are highly similar morphologically and genetically. The main differences between these three species are their differentiation patterns in the h... Read More about PAG3 promotes the differentiation of bloodstream forms in Trypanosoma brucei and reveals the evolutionary relationship among the Trypanozoon trypanosomes.

Prevalence of Eimeria species, detected by ITS1-PCR, in broiler poultry farms located in seven provinces of northeastern Algeria. (2022)
Journal Article
Djemai, S., Ayadi, O., Khelifi, D., Bellil, I., & Hide, G. (2022). Prevalence of Eimeria species, detected by ITS1-PCR, in broiler poultry farms located in seven provinces of northeastern Algeria. Tropical Animal Health and Production, 54(5), 250. https://doi.org/10.1007/s11250-022-03252-1

Coccidiosis is an important global chickens' disease which can cause serious economic losses in the poultry industry worldwide. Little is known about the extent of infection or diversity, of the causative agent Eimeria spp., in Algeria. A priority, t... Read More about Prevalence of Eimeria species, detected by ITS1-PCR, in broiler poultry farms located in seven provinces of northeastern Algeria..

Novel insertions in the mitochondrial maxicircle of Trypanosoma musculi, a mouse trypanosome (2022)
Journal Article
Wang, J., Lin, R., Zhang, X., Hide, G., Lun, Z., & Lai, D. (2022). Novel insertions in the mitochondrial maxicircle of Trypanosoma musculi, a mouse trypanosome. Parasitology, 1-42. https://doi.org/10.1017/S0031182022001019

Trypanosoma musculi is a, globally distributed, mouse-specific haemoflagellate, of the family Trypanosomatidae, which shares similar characteristics in morphology with Trypanosoma lewisi. The kinetoplast (mitochondrial) DNA of Trypanosomatidae flagel... Read More about Novel insertions in the mitochondrial maxicircle of Trypanosoma musculi, a mouse trypanosome.

Nile tilapia (Oreochromis niloticus) can be experimentally infected with both marine and freshwater fish trypanosomes. (2022)
Journal Article
Chen, K., Zhang, P., Yang, T., Wen, Y., Hide, G., Lun, Z., & Lai, D. (2022). Nile tilapia (Oreochromis niloticus) can be experimentally infected with both marine and freshwater fish trypanosomes. Experimental Parasitology, 239, 108288. https://doi.org/10.1016/j.exppara.2022.108288

Trypanosomes are haemoflagellates found in vertebrate species and many of them can cause death in infected hosts including fish and humans. With the development of high-density farming in marine and freshwater fish aquaculture systems, severe disease... Read More about Nile tilapia (Oreochromis niloticus) can be experimentally infected with both marine and freshwater fish trypanosomes..

iNOS is essential to maintain a protective Th1/Th2 response and the production of cytokines/chemokines against Schistosoma japonicum infection in rats (2022)
Journal Article
Shen, J., Yu, S., Peng, M., Lai, D., Hide, G., Wu, Z., & Lun, Z. (2022). iNOS is essential to maintain a protective Th1/Th2 response and the production of cytokines/chemokines against Schistosoma japonicum infection in rats. PLoS Neglected Tropical Diseases, 16(5), e0010403. https://doi.org/10.1371/journal.pntd.0010403

Humans and a wide range of mammals are generally susceptible to Schistosoma infection, while some rodents such as Rattus rats and Microtus spp are not. We previously demonstrated that inherent high expression levels of nitric oxide (NO), produced by... Read More about iNOS is essential to maintain a protective Th1/Th2 response and the production of cytokines/chemokines against Schistosoma japonicum infection in rats.

Transplantation of Gut Microbiota From High-Fat-Diet-Tolerant Cynomolgus Monkeys Alleviates Hyperlipidemia and Hepatic Steatosis in Rats. (2022)
Journal Article
Gao, J., Rao, J., Wei, Z., Xia, S., Huang, L., Tang, M., …Chen, J. (2022). Transplantation of Gut Microbiota From High-Fat-Diet-Tolerant Cynomolgus Monkeys Alleviates Hyperlipidemia and Hepatic Steatosis in Rats. Frontiers in Microbiology, 13, 876043. https://doi.org/10.3389/fmicb.2022.876043

Emerging evidence has been reported to support the involvement of the gut microbiota in the host's blood lipid and hyperlipidemia (HLP). However, there remains unexplained variation in the host's blood lipid phenotype. Herein a nonhuman primate HLP m... Read More about Transplantation of Gut Microbiota From High-Fat-Diet-Tolerant Cynomolgus Monkeys Alleviates Hyperlipidemia and Hepatic Steatosis in Rats..

The occurrence of malignancy in Trypanosoma brucei brucei by rapid passage in mice (2022)
Journal Article
Cai, X., Li, S., Zhang, P., Li, Z., Hide, G., Lai, D., & Lun, Z. (2022). The occurrence of malignancy in Trypanosoma brucei brucei by rapid passage in mice. Frontiers in Microbiology, 12, 806626. https://doi.org/10.3389/fmicb.2021.806626

Pleomorphic Trypanosoma brucei are best known for their tightly controlled cell growth and developmental program, which ensures their transmissibility and host fitness between the mammalian host and insect vector. However, after long-term adaptation... Read More about The occurrence of malignancy in Trypanosoma brucei brucei by rapid passage in mice.