Prof Geoff Hide's Outputs (14)

The relationship between the infection of Toxoplasma gondii and Alzheimer’s disease (2021)
Thesis
Alawfi, B. (2021). The relationship between the infection of Toxoplasma gondii and Alzheimer’s disease. (Thesis). University of Salford

Toxoplasma gondii is a zoonotic parasite that commonly causes infections in a variety of warm-blooded animals including humans. This parasite causes a disease referred to as toxoplasmosis. T. gondii infections are known to have a significant impact o... Read More about The relationship between the infection of Toxoplasma gondii and Alzheimer’s disease.

An investigation into Toxoplasma gondii infection and the expression of Arginase-1 and iNOS in human lung tissue (2021)
Thesis
Soothill, H. An investigation into Toxoplasma gondii infection and the expression of Arginase-1 and iNOS in human lung tissue. (Dissertation). University of Salford

This study aimed to investigate the relationship between Toxoplasma gondii infection and the expression of the immune modulating proteins Arginase-1 and iNOS in human lung biopsy samples. Previously, a 100% toxoplasmosis infection rate was found in 7... Read More about An investigation into Toxoplasma gondii infection and the expression of Arginase-1 and iNOS in human lung tissue.

Investigation into the genetic variation of Toll-Like Receptor 9 in cattle using both Sanger and next-generation sequencing from FTA-Cards (2020)
Thesis
Alqurashi, A. Investigation into the genetic variation of Toll-Like Receptor 9 in cattle using both Sanger and next-generation sequencing from FTA-Cards. (Thesis). University of Salford

The susceptibility or resistance to infectious diseases depends on the host immune response. The genetic variation of immune-relevant genes such as Toll-Like Receptor (TLR) genes is associated with susceptibility or resistance to the pathogen. In thi... Read More about Investigation into the genetic variation of Toll-Like Receptor 9 in cattle using both Sanger and next-generation sequencing from FTA-Cards.

Investigation into Toxoplasma gondii infection in relation to expression of neurodegenerative disease markers in natural mice populations (2020)
Thesis
Alshammari, A. (2020). Investigation into Toxoplasma gondii infection in relation to expression of neurodegenerative disease markers in natural mice populations. (Thesis). University of Salford

Toxoplasma gondii is a highly prevalent opportunistic protozoan parasite that has a remarkable capacity to infect humans and a range of warm-blooded animals. This research had two broad aims. Firstly, to investigating whether detection of T. gondii i... Read More about Investigation into Toxoplasma gondii infection in relation to expression of neurodegenerative disease markers in natural mice populations.

Investigating the relationship between lung cancer and the infection with the parasite Toxoplasma gondii (2020)
Thesis
Tarabulsi, M. Investigating the relationship between lung cancer and the infection with the parasite Toxoplasma gondii. (Thesis). University of Salford

Toxoplasma gondii is an obligate intracellular organism that has a worldwide distribution and is highly prevalent among animals and humans. Although usually asymptomatic, it can cause serious diseases in immunocompromised individuals such as pneumoni... Read More about Investigating the relationship between lung cancer and the infection with the parasite Toxoplasma gondii.

Investigation of genetic and epigenetic mechanisms of iNOS gene expression in infection of natural populations of Apodemus sylvaticus with the parasite Toxoplasma gondii (2020)
Thesis
Eshenshani, A. Investigation of genetic and epigenetic mechanisms of iNOS gene expression in infection of natural populations of Apodemus sylvaticus with the parasite Toxoplasma gondii. (Thesis). University of Salford

Toxoplasma gondii is a ubiquitous parasite that infects all warm blooded animals. It can cause pathology in both infected humans and infected animals. There have been many studies investigating the factors the affect infection of laboratory animals,... Read More about Investigation of genetic and epigenetic mechanisms of iNOS gene expression in infection of natural populations of Apodemus sylvaticus with the parasite Toxoplasma gondii.

An investigation in congenital transmission of Toxoplasma gondii as a potential mode of transmission in mice and humans (2011)
Thesis
Thomasson, D. An investigation in congenital transmission of Toxoplasma gondii as a potential mode of transmission in mice and humans. (Thesis). Salford : University of Salford

Toxoplasma gondii is a pathogenic Apicomplexan parasite with a worldwide
distribution in almost all warm blooded animals. The parasite is transmitted to hosts in
three ways; via oocysts that are passed from the definitive host the cat; by the... Read More about An investigation in congenital transmission of Toxoplasma gondii as a potential mode of transmission in mice and humans.

Investigations by PCR analysis of neospora caninum prevalence and co-infection with toxoplasma gondii in naturally infected populations (2009)
Thesis
Hughes, J. Investigations by PCR analysis of neospora caninum prevalence and co-infection with toxoplasma gondii in naturally infected populations. (Thesis). Salford : University of Salford

Neospora caninum and Toxoplasma gondii are closely related intracellular protozoan
parasites associated with abortion in mammals. TV! caninum was identified in 1984, described
as a new species in 1988 and often previously misidentified as T. gondii... Read More about Investigations by PCR analysis of neospora caninum prevalence and co-infection with toxoplasma gondii in naturally infected populations.

Investigation into pregnancy and toxoplasma gondii infection in Libya (2009)
Thesis
Abushahma, M. Investigation into pregnancy and toxoplasma gondii infection in Libya. (Thesis). University of Salford

Toxoplasma gone/// is a parasite discovered in 1908 by Nicolle and Manceaux;
they found a protozoan in tissue of a hamster-like rodent in laboratory of the Charles Nicolle at the Pasteur Institute in Tunisia. It is an obligate intracellular
protozo... Read More about Investigation into pregnancy and toxoplasma gondii infection in Libya.

Use of molecular tools to investigate the prevalence and transmission routes of Toxoplasma in woodmice and humans (2007)
Thesis
Gerwash, O. Use of molecular tools to investigate the prevalence and transmission routes of Toxoplasma in woodmice and humans. (Thesis). University of Salford

Toxoplasma gondii is an important pathogen of humans and domestic livestock and is
a major cause of abortion. It is widely distributed amongst mammals and birds and the
epidemiology of human disease is complex due to the interactions between human... Read More about Use of molecular tools to investigate the prevalence and transmission routes of Toxoplasma in woodmice and humans.

An investigation into the congenital transmission of Toxoplasma gondii within ovine populations managed on working sheep farms in the United Kingdom (2007)
Thesis
Morley, E. An investigation into the congenital transmission of Toxoplasma gondii within ovine populations managed on working sheep farms in the United Kingdom. (Thesis). Salford : University of Salford

Toxoplasma gondii is an economically important parasite that can cause spontaneous
abortion in sheep and humans. The importance of the different transmission routes of
the parasite is unclear. However, three routes are recognised: (1) shedding of... Read More about An investigation into the congenital transmission of Toxoplasma gondii within ovine populations managed on working sheep farms in the United Kingdom.

The use of molecular biological tools to investigate transmission routes and epidemiology of Toxoplasma gondii (2005)
Thesis
Williams, R. The use of molecular biological tools to investigate transmission routes and epidemiology of Toxoplasma gondii. (Thesis). Salford : University of Salford

Toxoplasma gondii is a major cause of abortion in humans and livestock. This work focuses on three main areas. Firstly, an investigation of congenital transmission of T. gondii in sheep. Using SAG1 PCR as a detection system, high levels of congenital... Read More about The use of molecular biological tools to investigate transmission routes and epidemiology of Toxoplasma gondii.

The molecular epidemiology of Toxoplasma gondii with specific reference to transmissions in sheep (2003)
Thesis
Duncanson, P. The molecular epidemiology of Toxoplasma gondii with specific reference to transmissions in sheep. (Thesis). Salford : University of Salford

Much research has been conducted on the life cycle of T. gondii by means of
investigation of experimentally infected animals. However, much less has been
achieved in studies of naturally infected populations. In particular, controversy
surrounds t... Read More about The molecular epidemiology of Toxoplasma gondii with specific reference to transmissions in sheep.

Development of PCR based techniques for the characterisation of Trypanosoma brucei strains from East Africa (2002)
Thesis
Tilley, A. Development of PCR based techniques for the characterisation of Trypanosoma brucei strains from East Africa. (Thesis). Salford : University of Salford

Human trypanosomiasis in east Africa, caused by Trypanosoma brucei rhodesiense,
occurs in specific foci that alternate between endemic and epidemic states.
Identification of T.b. rhodesiense is complicated as it also circulates in cattle
rese... Read More about Development of PCR based techniques for the characterisation of Trypanosoma brucei strains from East Africa.