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Gene-rich large deletions are overrepresented in POAG patients of Indian and Caucasian origins (2014)
Journal Article
Kaurani, L., Vishal, M., Kumar, D., Sharma, A., Mehani, B., Sharma, C., …Mukhopadhyay, A. (2014). Gene-rich large deletions are overrepresented in POAG patients of Indian and Caucasian origins. https://doi.org/10.1167/iovs.14-14339

PURPOSE: Large copy number variations (CNV) can contribute to increased burden for neurodegenerative diseases. In this study, we analyzed the genome-wide burden of large CNVs > 100 kb in primary open angle glaucoma (POAG), a neurodegenerative diseas... Read More about Gene-rich large deletions are overrepresented in POAG patients of Indian and Caucasian origins.

Formation of thick aminophenyl films from aminobenzenediazonium ion in the absence of a reduction source (2014)
Journal Article
Simons, B., Lehr, J., Garrett, D., & Downard, A. (2014). Formation of thick aminophenyl films from aminobenzenediazonium ion in the absence of a reduction source. Langmuir, 30(17), 4989-4996. https://doi.org/10.1021/la501217n

Aminophenyl films, electrografted to conducting substrates from a solution of the corresponding diazonium ion, are a useful platform for building up functional surfaces. In our hands, reproducible preparation of aminophenyl films via electrografting... Read More about Formation of thick aminophenyl films from aminobenzenediazonium ion in the absence of a reduction source.

JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease (2014)
Journal Article
Li, J., Kent, D., Godfrey, A., Manning, H., Nangalia, J., Aziz, A., …Green, A. (2014). JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease. Blood, 123(20), 3139-3151. https://doi.org/10.1182/blood-2013-06-510222

Genomic regions of acquired uniparental disomy (UPD) are common in malignancy and frequently harbor mutated oncogenes. Homozygosity for such gain-of-function mutations is thought to modulate tumor phenotype, but direct evidence has been elusive. Poly... Read More about JAK2V617F homozygosity drives a phenotypic switch in myeloproliferative neoplasms, but is insufficient to sustain disease.

Increased susceptibility to Trichuris muris infection and exacerbation of colitis in Mdr1a-/- mice (2014)
Journal Article
exacerbation of colitis in Mdr1a-/- mice. World Journal of Gastroenterology, 20(7), 1797-1806. https://doi.org/10.3748/wjg.v20.i7.1797

AIM: To investigate the influence of Trichuris muris (T. muris ) infection in a mouse model of genetic susceptibility to inflammatory bowel disease, Mdr1a-/-. METHODS: Mdr1a-/- mice were housed under specific pathogen free conditions to slow the... Read More about Increased susceptibility to Trichuris muris infection and exacerbation of colitis in Mdr1a-/- mice.

Toxoplasma gondii: Prevalence in species and genotypes of British bats (Pipistrellus pipistrellus and P. pygmaeus) (2014)
Journal Article
Dodd, N. S., Lord, J. S., Jehle, R., Parker, S., Parker, F., Brooks, D. R., & Hide, G. (2014). Toxoplasma gondii: Prevalence in species and genotypes of British bats (Pipistrellus pipistrellus and P. pygmaeus). Experimental Parasitology, 139, 6-11. https://doi.org/10.1016/j.exppara.2014.02.007

Few studies have investigated Toxoplasma gondii infections in bat populations and none have reported its presence in protected British bat species. Using a collection of dead/euthanased bats collected from Lancashire, UK, two species of bats (Pipis... Read More about Toxoplasma gondii: Prevalence in species and genotypes of British bats (Pipistrellus pipistrellus and P. pygmaeus).

Toxoplasma gondii : prevalence in species and genotypes of British bats (Pipistrellus pipistrellus and P. pygmaeus) (2014)
Journal Article
Dodd, N., Lord, J., Jehle, R., Parker, S., Parker, F., Brooks, D., & Hide, G. (2014). Toxoplasma gondii : prevalence in species and genotypes of British bats (Pipistrellus pipistrellus and P. pygmaeus). Experimental Parasitology, 139, 6-11. https://doi.org/10.1016/j.exppara.2014.02.007

Few studies have investigated Toxoplasma gondii infections in bat populations and none have reported its presence in protected British bat species. Using a collection of dead/euthanased bats collected from Lancashire, UK, two species of bats (Pipis... Read More about Toxoplasma gondii : prevalence in species and genotypes of British bats (Pipistrellus pipistrellus and P. pygmaeus).

CAPER, a novel regulator of human breast cancer progression (2014)
Journal Article
Mercier, I., Gonzales, D., Quann, K., Pestell, T., Molchansky, A., Sotgia, F., …Jasmin, J. (2014). CAPER, a novel regulator of human breast cancer progression. Cell Cycle, 13(8), 1256-1264. https://doi.org/10.4161/cc.28156

CAPE R is an estrogen receptor (ER) co-activator that was recently shown to be involved in human breast cancer pathogenesis. Indeed, we reported increased expression of CAPE R in human breast cancer specimens. We demonstrated that CAPE R was undete... Read More about CAPER, a novel regulator of human breast cancer progression.

Label-free capacitive diagnostics : exploiting local redox probe state occupancy (2014)
Journal Article
Lehr, J., Fernandes, F., Bueno, P., & Davis, J. (2014). Label-free capacitive diagnostics : exploiting local redox probe state occupancy. Analytical Chemistry, 86(5), 2559-2564. https://doi.org/10.1021/ac403727h

An electrode surface confined redox group contributes to a substantial potential-dependent interfacial charging that can be sensitively probed and frequency-resolved by impedance-derived capacitance spectroscopy. In utilizing the sensitivity of this... Read More about Label-free capacitive diagnostics : exploiting local redox probe state occupancy.

Colloidal interactions induced by overlap of mixed protein+polysaccharide interfacial layers (2014)
Journal Article
Ettelaie, R., & Akinshina, A. (2014). Colloidal interactions induced by overlap of mixed protein+polysaccharide interfacial layers. Food Hydrocolloids, 42(Part 1), 106-117. https://doi.org/10.1016/j.foodhyd.2014.01.020

Colloidal interaction potentials induced by the overlap of mixed protein + polysaccharide interfacial layers, formed solely as a result of electrostatic attraction between these two biopolymers, have been calculated using the Self Consistent Field Th... Read More about Colloidal interactions induced by overlap of mixed protein+polysaccharide interfacial layers.

Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth (2014)
Journal Article
Martinez-Outschoorn, U., Lisanti, M., & Sotgia, F. (2014). Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth. Seminars in Cancer Biology, 25, 47-60. https://doi.org/10.1016/j.semcancer.2014.01.005

Fibroblasts are the most abundant “non-cancerous” cells in tumors. However, it remains largely unknown how these cancer-associated fibroblasts (CAFs) promote tumor growth and metastasis, driving chemotherapy resistance and poor clinical outcome. Th... Read More about Catabolic cancer-associated fibroblasts transfer energy and biomass to anabolic cancer cells, fueling tumor growth.

Bioart (2014)
Book Chapter
Miah, A. (2014). Bioart. In R. Ranisch, & S. Sorgner (Eds.), Post- and transhumanism : an introduction (227-240). Berlin: Peter Lang

This chapter makes explicit the association of certain art forms and art works to trans- and posthumanist ideas, which have become constitutive of the political, cultural and philosophical differences and similarities that exist between these conc... Read More about Bioart.

The Olympic movement and new media (2014)
Book
Miah, A., Belousov, L., & Zolotarev, A. (2014). The Olympic movement and new media. Moscow: Russian International Olympic University

This book is devoted to the trends in the development of digital media and their impact on coverage of the Olympic Games and the promotion of Olympic values. The research for the book was carried out through content collection and analysis of social... Read More about The Olympic movement and new media.

Recent advances in studies of polymicrobial interactions in oral biofilms (2013)
Journal Article
James, C. (2013). Recent advances in studies of polymicrobial interactions in oral biofilms. Current Oral Health Reports, 1(1), 59-69. https://doi.org/10.1007/s40496-013-0006-3

The oral cavity supports a complex and finely balanced consortium of microbial species, many of which cooperate within structured biofilms. These communities develop through multitudinous synergistic and antagonistic interspecies relationships. Chang... Read More about Recent advances in studies of polymicrobial interactions in oral biofilms.

Somatic CALR Mutations in myeloproliferative neoplasms with nonmutated JAK2 (2013)
Journal Article
Nangalia, J., Massie, C., Baxter, E., Nice, F., Gundem, G., Wedge, D., …Aziz, A. E. A. (2013). Somatic CALR Mutations in myeloproliferative neoplasms with nonmutated JAK2. New England Journal of Medicine, 369(25), 2391-2405. https://doi.org/10.1056/NEJMoa1312542

BACKGROUND: Somatic mutations in the Janus kinase 2 gene (JAK2) occur in many myeloproliferative neoplasms, but the molecular pathogenesis of myeloproliferative neoplasms with nonmutated JAK2 is obscure, and the diagnosis of these neoplasms remains... Read More about Somatic CALR Mutations in myeloproliferative neoplasms with nonmutated JAK2.

JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: Connecting fibrosis, inflammation, and stemness for cancer prevention (2013)
Journal Article
Lisanti, M., Reeves, K., Peiris-Pagès, M., Chadwick, A., Sanchez-Alvarez, R., Howell, A., …Sotgia, F. (2014). JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: Connecting fibrosis, inflammation, and stemness for cancer prevention. Cell Cycle, 13(4), 580-599. https://doi.org/10.4161/cc.27379

Mammography is an important screening modality for the early detection of DCIS and breast cancer lesions. More specifically, high mammographic density is associated with an increased risk of breast cancer. However, the biological processes underlying... Read More about JNK1 stress signaling is hyper-activated in high breast density and the tumor stroma: Connecting fibrosis, inflammation, and stemness for cancer prevention.

Toxoplasma gondii infection in the peritoneal macrophages of rats treated with glucocorticoids (2013)
Journal Article
Wang, T., Gao, J., Yi, S., Geng, G., Gao, X., Shen, J., …Lun, Z. (2014). Toxoplasma gondii infection in the peritoneal macrophages of rats treated with glucocorticoids. Parasitology Research, 113(1), 351-358. https://doi.org/10.1007/s00436-013-3661-3

It is well known that toxoplasmosis can be life threatening to immunocompromised individuals such as AIDS and organ transplantation patients. Glucocorticoids (GCs) are widely used in the clinic for the treatment of autoimmune diseases and organ t... Read More about Toxoplasma gondii infection in the peritoneal macrophages of rats treated with glucocorticoids.

Preparation and characterization of au nanoparticles capped with mercaptocarboranyl clusters (2013)
Journal Article
M. Cioran, A., Teixidor, F., Krpetic, Ž., Brust, M., & Viñas, C. (2014). Preparation and characterization of au nanoparticles capped with mercaptocarboranyl clusters. Dalton Transactions, 43(13), 5054-5061. https://doi.org/10.1039/C3DT52872C

The preparation of 3–4 nm and 10 nm gold nanoparticles capped with neutral carborane-based mercaptocarboranes, via two different preparative routes, is reported. The resulting boron-enriched nanomaterials exhibit complete dispersibility in water, ope... Read More about Preparation and characterization of au nanoparticles capped with mercaptocarboranyl clusters.

Idiopathic pulmonary fibrosis is strongly associated with productive infection by herpesvirus saimiri (2013)
Journal Article
herpesvirus saimiri. Modern Pathology, 27, 851-862. https://doi.org/10.1038/modpathol.2013.198

Idiopathic pulmonary fibrosis is a fatal disease without effective therapy or diagnostic test. To investigate a potential role for c�herpesviruses in this disease, 21 paraffin-embedded lung biopsies from patients diagnosed with idiopathic pulmonary... Read More about Idiopathic pulmonary fibrosis is strongly associated with productive infection by herpesvirus saimiri.

Dog ownership, dog behaviour and transmission of Echinococcus spp. in the Alay Valley, southern Kyrgyzstan (2013)
Journal Article
van Kesteren, F., Mastin, A., Mytynova, B., Ziadinov, I., Boufana, B., Torgerson, P., …Craig, P. (2013). Dog ownership, dog behaviour and transmission of Echinococcus spp. in the Alay Valley, southern Kyrgyzstan. Parasitology, 140(13), 1674-1684. https://doi.org/10.1017/S0031182013001182

Echinococcosis is a re-emerging zoonotic disease in Kyrgyzstan, and the incidence of human infection has increased substantially since the collapse of the Soviet Union in 1991. Domestic dogs are hosts of Echinococcus spp. and play an important role i... Read More about Dog ownership, dog behaviour and transmission of Echinococcus spp. in the Alay Valley, southern Kyrgyzstan.